Table 1 Results of various biological assays on compounds 3–9
Compounds | IC50 ± SEM [μM] | |||
|---|---|---|---|---|
Anticancer activity (PC-3 cell line) | DPPH radical scavenging assay | ß-Glucuronidase inhibition | α-Glucosidase inhibition | |
3 | >30 | 56.26 ± 3.18 | NA | NA |
4a | >30 | NA | - | - |
4b | >30 | NA | NA | NA |
5a | >30 | NA | 0.130 ± 0.019 | - |
5b | >30 | NA | 19.9 ± 0.285 | - |
6 | >30 | NA | 1.2 ± 0.0785 | - |
7 | >30 | NA | NA | - |
8a | >30 | - | 1.2 ± 0.0785 | 13.2 ± 0.34 |
8b | 24.213 ± 0.29 | - | NA | 14.1 ± 0.28 |
9a | >30 | NA | 0.003 ± 0.09 | NA |
9b | >30 | NA | NA | - |
Std. | Doxorubicin 0.91 ± 0.1 | N-Acetylcysteine 106 ± 1.1 | D-Saccharic acid 1,4- lactone 45.75 ± 2.16 | Acarbose 841 ± 1.7 |