From: Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors
IC50 (µM)
VEGFR-2
FGFR-1
BRAF
8u
0.93 ± 0.10
3.74 ± 0.34
0.25 ± 0.03
Sorafenib
0.10 ± 0.01
0.58 ± 0.10 [62]
0.02 ± 0.002