Table 16 Anticancer activity results of most active compound b2
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compound | CNS cancer cell lines | 10−5 M concentration | Ovarian cancer cell lines | 10−5 M concentration |
|---|---|---|---|---|
b2 | SF-268 | 2.95 | IGROV1 | 7.71 |
SF-295 | 9.79 | OVCAR-3 | 6.34 | |
SF-539 | 3.99 | OVCAR-4 | 3.42 | |
SNB-19 | 5.42 | OVCAR-8 | 4.92 | |
SNB-57 | 2.49 | – | – | |
U-251 | 3.58 | – | – |