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Table 4 Pharmacokinetic parameters of bergapten after intravenous administration of 5 mg kg−1 (n = 8, mean ± SD)

From: The pharmacokinetics, bioavailability and excretion of bergapten after oral and intravenous administration in rats using high performance liquid chromatography with fluorescence detection

Parameters

Low (5 mg kg−1)

Tmax (h)

0.0333

Cmax (ng mL−1)

2080 ± 484

AUC(0–tn) (ng mL−1 h−1)

4391 ± 1363

AUC(0–∞) (ng mL−1 h−1)

4474 ± 1323

V/F (L)

0.0027 ± 0.0006

T1/2α (h)

1.74 ± 0.21

MRT(0–tn) (h)

1.80 ± 0.10

MRT(0–∞) (h)

4.05 ± 3.81

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BMC Chemistry

ISSN: 2661-801X

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