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Table 1 Antibacterial activity of compounds 8a–k (concentration used 250 μg/mL of DMSO)

From: Synthesis and antibacterial activity of novel 5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine-2-carbohydrazide derivatives

Compound no.

Zones of inhibition of compounds 8a–k in mm

Gram negative

Gram positive

E. coli MTCC 443

P. aeruginosa MTCC 424

S. aureus MTCC 96

S. pyogenes MTCC 442

8a

25

19

24

17

8b

27

20

23

18

8c

26

19

23

17

8d

33

24

29

24

8e

30

25

30

22

8f

30

23

31

22

8g

20

16

19

13

8h

21

15

19

14

8i

8j

8k

Standard drug: Norfloxacin

29

23

28

21