Skip to main content

Table 5 Robustness of naphazoline hydrochloride

From: A validated stability-indicating HPLC method for the simultaneous determination of pheniramine maleate and naphazoline hydrochloride in pharmaceutical formulations

Chromatographic condition

Assay %

tR (min)

Theoretical plates

Symmetry

Flow rate (0.9 mL min-1)

101.5

6.565

6534

0.91

Flow rate (1 mL min-1)

99.9

6.154

6745

0.93

Flow rate (1.1 mL min-1)

103.6

5.331

6521

0.88

Buffer: Methanol (70:30)

99.7

6.944

6346

0.90

Buffer: Methanol (68:32)

99.2

6.154

6351

0.89

Buffer: Methanol (65:35)

98.1

5.681

6566

0.86

Buffer (pH 2.6)

100.9

5.764

6812

0.85

Buffer (pH 2.8)

101.4

6.148

6745

0.89

Buffer (pH 3.0)

100.2

6.145

6625

0.87