From: Ultrasonic irradiation assisted efficient regioselective synthesis of CF3-containing pyrazoles catalyzed by Cu(OTf)2/Et3N
Entry
Catalyst
Loading (mol%)
Time (min.)
Yields (%)
1
None
-
180
No reaction
2
EtONa
100
60
Traces
3
Et3N
5
45
73
4
10
67
Cu(OTf)2
6
7
Cu(OTf)2/ Et3N
5:5
90
8
10:5