Comp NO. | Compound concentration (μM) | IC50(μM) | |||
---|---|---|---|---|---|
10 μM | 25 μM | 50 μM | 100 μM | ||
Surviving fraction (Mean ± S.E.)* | |||||
Doxorubicin | 0.721 ± 0.02 | 0.546 ± 0.02 | 0.461 ± 0.01 | 0.494 ± 0.03 | 71.80 |
2 | 0.727 ± 0.134 | 0.427 ± 0.055 | 0.307 ± 0.029 | 0.317 ± 0.021 | 46.57 |
3 | 0.793 ± 0.055 | 0.454 ± 0.097 | 0.292 ± 0.008 | 0.332 ± 0.050 | 52.45 |
4 | 0.840 ± 0.063 | 0.435 ± 0.035 | 0.403 ± 0.015 | 0.335 ± 0.082 | 54.37 |
5 | 0.906 ± 0.021 | 0.642 ± 0.059 | 0.428 ± 0.038 | 0.547 ± 0.046 | 81.22 |
6 | 0.732 ± 0.333 | 0.584 ± 0.046 | 0.406 ± 0.069 | 0.229 ± 0.097 | 49.65 |
7 | 0.761 ± 0.190 | 0.546 ± 0.123 | 0.254 ± 0.031 | 0.297 ± 0.048 | 47.83 |
8 | 0.830 ± 0.124 | 0.399 ± 0.082 | 0.199 ± 0.021 | 0.272 ± 0.005 | 42.56 |
9 | 0.649 ± 0.028 | 0.394 ± 0.339 | 0.207 ± 0.027 | 0.261 ± 0.049 | 37.29 |
10 | 0.609 ± 0.059 | 0.479 ± 0.095 | 0.332 ± 0.058 | 0.316 ± 0.064 | 45.45 |
11 | 0.747 ± 0.197 | 0.359 ± 0.052 | 0.153 ± 0.020 | 0.189 ± 0.002 | 35.40 |
12 | 0.604 ± 0.075 | 0.232 ± 0.019 | 0.376 ± 0.089 | 0.312 ± 0.029 | 40.12 |
13 | 0.650 ± 0.184 | 0.401 ± 0.016 | 0.253 ± 0.021 | 0.401 ± 0.017 | 45.77 |
14 | 0.875 ± 0.066 | 0.580 ± 0.046 | 0.336 ± 0.049 | 0.467 ± 0.047 | 65.58 |
15 | 0.886 ± 0.047 | 0.423 ± 0.024 | 0.259 ± 0.054 | 0.389 ± 0.047 | 52.48 |
16 | 0.669 ± 0.114 | 0.539 ± 0.088 | 0.276 ± 0.064 | 0.259 ± 0.080 | 44.62 |
17 | 0.509 ± 0.235 | 0.230 ± 0.139 | 0.300 ± 0.134 | 0.279 ± 0.065 | 29.86 |
18 | 0.865 ± 0.057 | 0.615 ± 0.048 | 0.232 ± 0.046 | 0.286 ± 0.071 | 50.74 |
19 | 0.815 ± 0.042 | 0.545 ± 0.109 | 0.264 ± 0.044 | 0.336 ± 0.096 | 51.48 |
20 | 0.703 ± 0.189 | 0.427 ± 0.194 | 0.251 ± 0.026 | 0.374 ± 0.085 | 46.26 |
21 | 0.941 ± 0.020 | 0.472 ± 0.209 | 0.199 ± 0.090 | 0.278 ± 0.108 | 47.49 |
22 | 0.653 ± 0.291 | 0.574 ± 0.180 | 0.337 ± 0.116 | 0.359 ± 0.044 | 52.74 |
23 | 0.878 ± 0.032 | 0.563 ± 0.065 | 0.276 ± 0.031 | 0.389 ± 0.058 | 56.37 |
24 | 0.648 ± 0.329 | 0.280 ± 0.154 | 0.174 ± 0.105 | 0.194 ± 0.065 | 30.99 |