Tabletsa | Recovery (% ± SD)b | t-valuec | F-valuec |
---|
| Proposed method | Reference methodd | | |
---|
Sensipar | 102.23 ± 1.27 | 101.43 ± 1.35 | 0.97 | 1.14 |
Mimpara | 100.80 ± 1.60 | 100.10 ± 1.30 | 1.71 | 1.91 |
- a Labeled to contain 60 mg CIN per tablet.
- b Values are mean of five determinations.
- c The tabulated t- and F-values at 95% confidence limit are 2.31 and 6.61, respectively.
- d Reference method: Khalil NY, Wani TA, Darwish IA: An ICH-validated high-performance liquid chromatographic method with fluorescence detection for determination of cinacalcet hydrochloride in tablets and plasma, unpublished.