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  1. Content type: Research article

    The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, s...

    Authors: David R. Lisgarten, Rex A. Palmer, Carina M. C. Lobley, Claire E. Naylor, Babur Z. Chowdhry, Zakieh I. Al-Kurdi, Adnan A. Badwan, Brendan J. Howlin, Nicholas C. J. Gibbons, José W. Saldanha, John N. Lisgarten and Ajit K. Basak

    Citation: Chemistry Central Journal 2017 11:73

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  2. Content type: Research article

    Tumor angiogenesis, essential for tumor growth and metastasis, is tightly regulated by VEGF/VEGFR and PDGF/PDGFR pathways, and therefore blocking those pathways is a promising therapeutic target. Compared to s...

    Authors: Ting-Hsuan Yang, Chun-I Lee, Wen-Hsin Huang and An-Rong Lee

    Citation: Chemistry Central Journal 2017 11:72

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  3. Content type: Research article

    Kinetics and a mechanistic investigation of the reaction between dimethyl acetylenedicarboxcylate (DMAD) and saccharin (NH heterocyclic compound) has been spectrally studied in methanol environment in the presen...

    Authors: Sayyed Mostafa Habibi-Khorassani, Mehdi Shahraki and Mahdieh Darijani

    Citation: Chemistry Central Journal 2017 11:71

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  4. Content type: Research article

    Multi drug-resistant and mycobacterial infections are a major public health challenge, leading to high mortality and socioeconomic burdens through worldwide. Novel therapeutics are necessary to treat the drug ...

    Authors: Mohana Rao Anguru, Ashok Kumar Taduri, Rama Devi Bhoomireddy, Malathi Jojula and Shravan Kumar Gunda

    Citation: Chemistry Central Journal 2017 11:68

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  5. Content type: Research article

    Uracil derivatives have a great attraction because they play an important role in pharmacological activities. Pyrimidodiazepines, lumazines, triazolopyrimidines and xanthines have significant wide spectrum act...

    Authors: Samar A. El-Kalyoubi, Eman A. Fayed and Ahmed S. Abdel-Razek

    Citation: Chemistry Central Journal 2017 11:66

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    The Erratum to this article has been published in Chemistry Central Journal 2017 11:69

  6. Content type: Methodology

    Experimental approaches for determining the metabolic properties of the drug candidates are usually expensive, time-consuming and labor intensive. There is a great deal of interest in developing computational ...

    Authors: Jiajia Meng, Shiliang Li, Xiaofeng Liu, Mingyue Zheng and Honglin Li

    Citation: Chemistry Central Journal 2017 11:65

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  7. Content type: Research article

    Pickled soybeans or vinegar beans have long been used as a folk remedy and also a supplemental nutritional source in Korea. In general the pickling process in vinegar improves the digestibility of soybeans as ...

    Authors: Ill-Min Chung, Jin-Young Oh and Seung-Hyun Kim

    Citation: Chemistry Central Journal 2017 11:64

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  8. Content type: Research article

    This study has demonstrated the use of crystallography, topology and graph set analysis in the description and classification of the complex hydrogen bonded network of triamterene. The aim is to give a brief o...

    Authors: David S. Hughes, Amit Delori, Abida Rehman and William Jones

    Citation: Chemistry Central Journal 2017 11:63

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  9. Content type: Research article

    A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed and validated for the determination of brimonidine tartrate in brimonidine tartrat...

    Authors: Jianguo Sun, Xiuwen Zhang and Taomin Huang

    Citation: Chemistry Central Journal 2017 11:62

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  10. Content type: Review

    In these recent years, magnetite (Fe3O4) has witnessed a growing interest in the scientific community as a potential material in various fields of application namely in catalysis, biosensing, hyperthermia treatme...

    Authors: Essy Kouadio Fodjo, Koffi Mouroufié Gabriel, Brou Yapi Serge, Dan Li, Cong Kong and Albert Trokourey

    Citation: Chemistry Central Journal 2017 11:58

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  11. Content type: Research article

    The black turtle bean (BTB) is most widely consumed legume all over the world having anticancer activity. The aim of the study was to analyse the apoptotic effects of BTB extracts on human breast cancer cell l...

    Authors: Suresh Kumar, Vinay Kumar Sharma, Savita Yadav and Sharmistha Dey

    Citation: Chemistry Central Journal 2017 11:56

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  12. Content type: Research article

    Clinacanthus nutans Lindau is a well-known plant, native to tropical Asian countries. Reports on this plant that is rich in phenolic compounds have focused on its therapeutic anti-infl...

    Authors: Intan Soraya Che Sulaiman, Mahiran Basri, Hamid Reza Fard Masoumi, Wei Jian Chee, Siti Efliza Ashari and Maznah Ismail

    Citation: Chemistry Central Journal 2017 11:54

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  13. Content type: Research article

    Pyrazolo[1,5-a]pyrimidines are purine analogues. They have beneficial properties as antimetabolites in purine biochemical reactions. This division compounds have attracted wide pharmaceutical interest because of ...

    Authors: Nadia A. Abdelriheem, Yasser H. Zaki and Abdou O. Abdelhamid

    Citation: Chemistry Central Journal 2017 11:53

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  14. Content type: Research article

    Due to their interesting and versatile biological activity, thiophene-containing compounds have attracted the attention of both chemists and medicinal chemists. Some of these compounds have anticancer, antibac...

    Authors: Yahia N. Mabkhot, Salim S. Al-Showiman, Saied M. Soliman, Hazem A. Ghabbour, Murad A. AlDamen and Mohammad S. Mubarak

    Citation: Chemistry Central Journal 2017 11:51

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  15. Content type: Research article

    The diacylhydrazine derivatives have attracted considerable attention in recently years due to their simple structure, low toxicity, and high insecticidal selectivity. As well as 3-bromo-1-(3-chloropyridin-2-y...

    Authors: Yanyan Wang, Fangzhou Xu, Gang Yu, Jun Shi, Chuanhui Li, A’li Dai, Zhiqian Liu, Jiahong Xu, Fenghua Wang and Jian Wu

    Citation: Chemistry Central Journal 2017 11:50

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  16. Content type: Research article

    Morphologically controlled synthesis of ferric oxide nano/micro particles has been carried out by using solvothermal route. Structural characterization displays that the predominant morphologies are porous hol...

    Authors: Muhammad Ramzan Saeed Ashraf Janjua, Saba Jamil, Nazish Jahan, Shanza Rauf Khan and Saima Mirza

    Citation: Chemistry Central Journal 2017 11:49

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  17. Content type: Research article

    The quinazoline are an important class of medicinal compounds that possess a number of biological activities like anticancer, anticonvulsant and antioxidant etc.

    Authors: Danah S. Al-Shamary, Monirah A. Al-Alshaikh, Nabila Abdelshafy Kheder, Yahia Nasser Mabkhot and Syed Lal Badshah

    Citation: Chemistry Central Journal 2017 11:48

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  18. Content type: Review

    Gadolinium (Gd)-based contrasts remain one of the most accepted contrast agents for magnetic resonance imaging, which is among the world most recognized noninvasive techniques employed in clinical diagnosis of...

    Authors: Muhammad Sani Usman, Mohd Zobir Hussein, Sharida Fakurazi and Fathinul Fikri Ahmad Saad

    Citation: Chemistry Central Journal 2017 11:47

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  19. Content type: Research article

    Vandetanib (VNT) is a new oral tyrosine kinase inhibitor that acts mainly by inhibiting vascular endothelial growth factor receptor (VEGFR). Fast, specific, sensitive and validated LC–MS/MS was established for...

    Authors: Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish and Mohamed W. Attwa

    Citation: Chemistry Central Journal 2017 11:45

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  20. Content type: Research article

    Superabsorbent hydrogels show a large potential in a wide array of applications due to their unique properties. Carboxymethylcellulose (CMC) is a commercially available water-soluble cellulose derivative of ma...

    Authors: Tamás Fekete, Judit Borsa, Erzsébet Takács and László Wojnárovits

    Citation: Chemistry Central Journal 2017 11:46

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  21. Content type: Research article

    Developing an efficient lipophilization reaction system for phenolic derivatives could enhance their applications in food processing. Low solubility of phenolic acids reduces the efficiency of phenolic derivat...

    Authors: Somayeh Gholivand, Ola Lasekan, Chin Ping Tan, Faridah Abas and Leong Sze Wei

    Citation: Chemistry Central Journal 2017 11:44

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  22. Content type: Research article

    Analysis of complex mixture containing three or more components represented a challenge for analysts. New smart spectrophotometric methods have been recently evolved with no limitation. A study of different no...

    Authors: Ekram H. Mohamed, Hayam M. Lotfy, Maha A. Hegazy and Shereen Mowaka

    Citation: Chemistry Central Journal 2017 11:43

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  23. Content type: Research article

    A series of novel N-(2, 6-dimethoxypyrimidin-4-yl)-4-(3-(aryl)thioureido) benzenesulfonamides 3at was synthesized by the addition of N-(2,6-dimethoxypyrimidin-4-yl)-4-isothiocyanatobenzenesulfonamide 2 to the ap...

    Authors: Mostafa M. Ghorab, Mohamed S. A. El-Gaby, Aiten M. Soliman, Mansour S. Alsaid, Marwa M. Abdel-Aziz and Mahmoud M. Elaasser

    Citation: Chemistry Central Journal 2017 11:42

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  24. Content type: Research article

    Quantitative structure activity relationship was carried out to study a series of PIM1 and PIM2 inhibitors. The present study was performed on twenty-five substituted 5-(1H-indol-5-yl)-1,3,4-thiadiazols as PIM...

    Authors: Adnane Aouidate, Adib Ghaleb, Mounir Ghamali, Samir Chtita, M’barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi

    Citation: Chemistry Central Journal 2017 11:41

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  25. Content type: Research article

    Four novel complexes [Co(H2O)4(sul)2] 1, [Co(2-ampy)2(sul)2] 2, [Co(H2O)2(1,10-phen) (sul)2] 3 and [Co(2,9-dimephen)(sul)2] 4 (sul = sulindac, 2-ampy = 2-amino pyridine, 1,10-phen = 1,10-phenanthroline and 2,9-di...

    Authors: Asia M. Shalash and Hijazi I. Abu Ali

    Citation: Chemistry Central Journal 2017 11:40

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  26. Content type: Research article

    Replacement of chloride ions in cyanuric chloride give several variants of 1,3,5-triazine derivatives which were investigated as biologically active small molecules. These compounds exhibit antimalarial, antim...

    Authors: Khadijah M. Al-Zaydi, Hosam H. Khalil, Ayman El-Faham and Sherine N. Khattab

    Citation: Chemistry Central Journal 2017 11:39

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  27. Content type: Research article

    Rice vinegar (RV) and white vinegar (WV) as daily flavoring, have also used as accessory in traditional Chinese medicine processing. As we know, the promoting blood circulation efficiency could be enhanced whe...

    Authors: Zhangchi Ning, Zhenli Liu, Zhiqian Song, Chun Wang, Yuanyan Liu, Jiahe Gan, Xinling Ma and Aiping Lu

    Citation: Chemistry Central Journal 2017 11:38

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  28. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. A combination of indacaterol maleate with glycopyrronium bromide has recently been approved as a once-daily m...

    Authors: Sahar Zayed and Fathalla Belal

    Citation: Chemistry Central Journal 2017 11:36

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  29. Content type: Research article

    Porphyra tenera (Kjellman, 1897) is the most common eatable red seaweed in Asia. In the present study, P. tenera volatile oil (PTVO) was extracted from dried P. tenera sheets that were...

    Authors: Jayanta Kumar Patra, Se-Weon Lee, Yong-Suk Kwon, Jae Gyu Park and Kwang-Hyun Baek

    Citation: Chemistry Central Journal 2017 11:34

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  30. Content type: Research article

    Natural based composites of hydroxyapatite/Gum Arabic designed for removal of toxic metal arsenic (III) from waste water were synthesized and evaluated. Several composites with various compositions were prepar...

    Authors: N. Akartasse, E. Mejdoubi, B. Razzouki, K. Azzaoui, S. Jodeh, O. Hamed, M. Ramdani, A. Lamhamdi, M. Berrabah, I. Lahmass, W. Jodeh and S. El Hajjaji

    Citation: Chemistry Central Journal 2017 11:33

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  31. Content type: Research article

    Various thiourea derivatives have been used as starting materials for compounds with better biological activities. Molecular modeling tools are used to explore their mechanism of action.

    Authors: Mostafa M. Ghorab, Mansour S. Alsaid, Mohamed S. A. El-Gaby, Mahmoud M. Elaasser and Yassin M. Nissan

    Citation: Chemistry Central Journal 2017 11:32

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  32. Content type: Research article

    A series of rare-earth bisphthalocyanines of praseodymium, samarium and gadolinium bearing 5-bromo-2-thienyl substituents were prepared for the first time.

    Authors: Jiří Černý, Lenka Dokládalová, Petra Horáková, Antonín Lyčka, Tomáš Mikysek and Filip Bureš

    Citation: Chemistry Central Journal 2017 11:31

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  33. Content type: Research article

    Acetone is an important solvent and widely used in the synthesis of drugs and polymers. Currently, acetone is mainly generated by the Cumene Process, which employs benzene and propylene as fossil raw materials...

    Authors: Clarissa Perdomo Rodrigues, Priscila da Costa Zonetti and Lucia Gorenstin Appel

    Citation: Chemistry Central Journal 2017 11:30

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  34. Content type: Preliminary communication

    Plants contain a myriad of metabolites which exhibit diverse biological activities. However, in-depth analyses of these natural products with current analytical platforms remains an undisputed challenge due to...

    Authors: Keabetswe Masike, Msizi I. Mhlongo, Shonisani P. Mudau, Ofentse Nobela, Efficient N. Ncube, Fidele Tugizimana, Mosotho J. George and Ntakadzeni E. Madala

    Citation: Chemistry Central Journal 2017 11:29

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  35. Content type: Research article

    Samples of natural clinoptilolite were modified by an acid–thermal method at nitric acid concentrations of 0.25, 0.5, 1.0, and 3.0 M and a contact time of 30 min. A series of catalysts, K2PdCl4–Cu(NO3)2–KBr/S (S ...

    Authors: Tatyana L. Rakitskaya, Tatyana A. Kiose, Kristina O. Golubchik, Alim A. Ennan and Vitalia Y. Volkova

    Citation: Chemistry Central Journal 2017 11:28

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  36. Content type: Research article

    Traditional fermented alcoholic beverages are indigenous to a particular area and are prepared by the local people using an age-old techniques and locally available raw materials. The main objective of this wo...

    Authors: Ayalew Debebe, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2017 11:27

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  37. Content type: Research article

    We aimed to enhance the solubility, dissolution properties, and skin-whitening ability of ferulic acid (FA) by preparing a ferulic acid–phospholipid complex (FA–PC). The properties and melanogenesis inhibition...

    Authors: Li Li, Yanhong Liu, Yan Xue, Jun Zhu, Xiaoyue Wang and Yinmao Dong

    Citation: Chemistry Central Journal 2017 11:26

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