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  1. Content type: Research Article

    A series of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives 10(af), 12(ac) and 14(ac) were synthesized and characterized by FTIR, 1H-NMR, mass spectral an...

    Authors: Vinaya Kambappa, G. K. Chandrashekara, N. D. Rekha, Prasanna D. Shivaramu and Komaraiah Palle

    Citation: Chemistry Central Journal 2017 11:122

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  2. Content type: Correction

    After the publication of this work [1] it was noticed that on page 3 of the article beginning in the paragraph—‘Hydrazide 14 is used as a key producer…’ the compound—“Not ethyl-N′-5-amino-1,3-diphenyl-1H-thieno[3...

    Authors: Mohamed A. M. Abdel Reheim and Safaa M. Baker

    Citation: Chemistry Central Journal 2017 11:123

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    The original article was published in Chemistry Central Journal 2017 11:112

  3. Content type: Research Article

    Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of...

    Authors: Xiao-Yang Zhou, Ling-Jing Yuan, Zhe Chen, Peng-Fei Tang, Xiang-Yu Li, Guo-Xin Hu and Jian-Ping Cai

    Citation: Chemistry Central Journal 2017 11:121

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  4. Content type: Research article

    A series of recently reported phenolic azo dyes 7a–e were prepared by coupling the thienyl diazonium sulfate of 3-Amino-4H-benzo[f]thieno[3,4-c](2H)chromen-4-one with selected diversely substituted phenolic and n...

    Authors: Joseph Tsemeugne, Emmanuel Sopbué Fondjo, Jean-de-Dieu Tamokou, Ignas Tonle, Irene Chinda Kengne, Arnaud Djintchui Ngongang, Stephen Tamekou Lacmata, Taoufik Rohand, Jules Roger Kuiate and Beibam Luc Sondengam

    Citation: Chemistry Central Journal 2017 11:119

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  5. Content type: Research article

    1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry.

    Authors: Mohamed Reda Aouad, Mariem Mohammed Mayaba, Arshi Naqvi, Sanaa K. Bardaweel, Fawzia Faleh Al-blewi, Mouslim Messali and Nadjet Rezki

    Citation: Chemistry Central Journal 2017 11:117

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  6. Content type: Research article

    Polysaccharides are structurally complex and essential constituents of life, and therefore, studies directed to these kinds of molecules have received scientific attention. Despite an easy availability of Dolicho...

    Authors: Shibani Basu, Manojit Ghosh, Rupam Kumar Bhunia, Jhuma Ganguly and Bimal K. Banik

    Citation: Chemistry Central Journal 2017 11:118

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  7. Content type: Research article

    The plant Alisma plantago-aquatica Linnaeus, which is widely distributed in southwest of China, is the main material of traditional Chinese medicine “Zexie”. It was used as folk medicine for immune-modulation, an...

    Authors: Ya-sheng Huang, Qi-qi Yu, Yin Chen, Min-jie Cheng and Li-ping Xie

    Citation: Chemistry Central Journal 2017 11:120

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  8. Content type: Research article

    The interaction of paeoniflorin with human serum albumin (HSA) was investigated using fluorescence, UV–vis absorption, circular dichroism (CD) spectra and molecular docking techniques under simulative physiolo...

    Authors: Liang Xu, Yan-Xi Hu, Yan-Cheng Li, Yu-Feng Liu, Li Zhang, Hai-Xin Ai and Hong-Sheng Liu

    Citation: Chemistry Central Journal 2017 11:116

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  9. Content type: Research article

    Acyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some p...

    Authors: Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh and Baljeet Singh Saharan

    Citation: Chemistry Central Journal 2017 11:115

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    The Correction to this article has been published in Chemistry Central Journal 2018 12:9

  10. Content type: Research article

    The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin...

    Authors: Zhaoyang Xia, Dongdong Li, Qing Li, Yan Zhang and Wenyi Kang

    Citation: Chemistry Central Journal 2017 11:114

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  11. Content type: Research article

    Many Geum species are known to be rich in biologically active compounds and therefore could be a source of new natural products with pharmacological potential. The medicinal plant Geum urbanum L. is widespread in...

    Authors: Lyudmila Dimitrova, Maya M. Zaharieva, Milena Popova, Nedelina Kostadinova, Iva Tsvetkova, Vassya Bankova and Hristo Najdenski

    Citation: Chemistry Central Journal 2017 11:113

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  12. Content type: Research article

    Some novel substituted pyrazolone, pyrazolo[3,4-c]pyridazine, pyrazolo[3,4-d]pyrimidine, pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidinone, thieno[3,2-c]pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3-d]pyrimidine derivative...

    Authors: Mohamed A. M. Abdel Reheim and Safaa M. Baker

    Citation: Chemistry Central Journal 2017 11:112

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    The Correction to this article has been published in Chemistry Central Journal 2017 11:123

  13. Content type: Research article

    This work compares the composition at different temperatures of gaseous phase of bergamot essential oil at equilibrium with the liquid phase. A new GC–MS methodology to determine quantitatively the volatile ar...

    Authors: Antonella Leggio, Vanessa Leotta, Emilia Lucia Belsito, Maria Luisa Di Gioia, Emanuela Romio, Ilaria Santoro, Domenico Taverna, Giovanni Sindona and Angelo Liguori

    Citation: Chemistry Central Journal 2017 11:111

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  14. Content type: Research article

    Blue corn is a cereal rich in phenolic compounds used to make blue tortillas. Tortillas are an important part of the Mexican diet. Blue corn and tortilla represent an important source of the natural antioxidan...

    Authors: Mónica Y. Herrera-Sotero, Carlos D. Cruz-Hernández, Carolina Trujillo-Carretero, Mauricio Rodríguez-Dorantes, Hugo S. García-Galindo, José L. Chávez-Servia, Rosa M. Oliart-Ros and Rosa I. Guzmán-Gerónimo

    Citation: Chemistry Central Journal 2017 11:110

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  15. Content type: Research article

    Myricetin and 1,3,4-thiadiazole derivatives were reported to exhibit favorable antiviral and antibacterial activities. Aiming to discover novel myricetin analogues with potent activities, a series of novel myr...

    Authors: Xinmin Zhong, Xiaobin Wang, Lijuan Chen, Xianghui Ruan, Qin Li, Juping Zhang, Zhuo Chen and Wei Xue

    Citation: Chemistry Central Journal 2017 11:106

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  16. Content type: Research article

    Khat (Catha edulis Forsk) is an evergreen shrub of the Celastraceae family. It is widely cultivated in Yemen and East Africa, where its fresh leaves are habitually chewed for their momentary pleasures and stimula...

    Authors: Minaleshewa Atlabachew, Bhagwan Singh Chandravanshi and Mesfin Redi-Abshiro

    Citation: Chemistry Central Journal 2017 11:107

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  17. Content type: Research article

    The main objective of this work was to synthesize novel compounds with a benzo[de][1,2,4]triazolo[5,1-a]isoquinoline scaffold by employing (dioxo-benzo[de]isoquinolin-2-yl) thiourea as a building block. Molecular...

    Authors: Hatem A. Abuelizz, Rashad Al-Salahi, Jamil Al-Asri, Jérémie Mortier, Mohamed Marzouk, Essam Ezzeldin, Azza A. Ali, Mona G. Khalil, Gerhard Wolber, Hazem A. Ghabbour, Abdulrahman A. Almehizia and Gehad A. Abdel Jaleel

    Citation: Chemistry Central Journal 2017 11:103

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  18. Content type: Research article

    Many heterocyclic compounds containing thiazole or 1,3,4-thiadiazole ring in their skeletons have been reported to possess various pharmacological activities especially anticancer activities.

    Authors: Sobhi M. Gomha, Mohamad R. Abdelaziz, Nabila A. Kheder, Hassan M. Abdel-aziz, Seham Alterary and Yahia N. Mabkhot

    Citation: Chemistry Central Journal 2017 11:105

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  19. Content type: Research article

    In order to improve the gelling properties of agarose, we modified it by methylation. The agarose was prepared from Gracilaria asiatica, G. bailinae, and G. lemaneiformis with alkaline, treated with diatomaceous ...

    Authors: Yangyang Gu, Kit-Leong Cheong and Hong Du

    Citation: Chemistry Central Journal 2017 11:104

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  20. Content type: Research article

    Jujube extract is commonly used as a food additive and flavoring. The unique jujube aroma and the mild sweet aroma of the extract are critical factors that determine product quality and affect consumer accepta...

    Authors: Shi-Hao Sun, Guo-Bi Chai, Peng Li, Jian-Ping Xie and Yue Su

    Citation: Chemistry Central Journal 2017 11:101

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  21. Content type: Review

    Over the past few decades, metal–organic frameworks (MOFs) have proved themselves as strong contenders in the world of porous materials, standing alongside established classes of compounds such as zeolites and...

    Authors: Alexander J. Tansell, Corey L. Jones and Timothy L. Easun

    Citation: Chemistry Central Journal 2017 11:100

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  22. Content type: Research article

    The combination between cetirizine (CET), phenylpropanolamine (PPA) and nimesulide (NMS) under trade name Nemeriv Cp tablet is prescribed for nasal congestion, cold, sneezing, and allergy. Among all published ...

    Authors: Fatma Ahmed Aly, Nahed EL-Enany, Heba Elmansi and Amany Nabil

    Citation: Chemistry Central Journal 2017 11:99

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  23. Content type: Research Article

    In this study, Ligustrum lucidum flowers as raw material, the extraction, isolation and coagulatory activity of polysaccharides were carried out for the first time. The crude polysaccharide was obtained by hot wa...

    Authors: Zhenhua Yin, Wei Zhang, Juanjuan Zhang and Wenyi Kang

    Citation: Chemistry Central Journal 2017 11:98

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  24. Content type: Research article

    This study focused on maximizing the extraction yield of total phenolics and flavonoids from Curcuma Zedoaria leaves as a function of time (80–120 min), temperature (60–80 °C) and ethanol concentration (70–90 v/v...

    Authors: Nur Fauwizah Azahar, Siti Salwa Abd Gani and Nor Fadzillah Mohd Mokhtar

    Citation: Chemistry Central Journal 2017 11:96

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  25. Content type: Research Article

    The plant biomass and agro-industrial wastes show great potential for their use as attractive low cost substrates in biotechnological processes. Wheat straw and corn cob as hemicellulosic substrates were acid ...

    Authors: Abdul Ghaffar, Muhammad Yameen, Nosheen Aslam, Fatima Jalal, Razia Noreen, Bushra Munir, Zahed Mahmood, Sadaf Saleem, Naila Rafiq, Sadia Falak, Imtiaz Mahmood Tahir, Muhammad Noman, Muhammad Umar Farooq, Samina Qasim and Farooq Latif

    Citation: Chemistry Central Journal 2017 11:97

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  26. Content type: Review

    The sunflower (Helianthus annuus L.) seed and sprout is a ubiquitous crop with abundant nutrients and biological activities. This review summarizes the nutritional and medical importance currently recognized but ...

    Authors: Shuangshuang Guo, Yan Ge and Kriskamol Na Jom

    Citation: Chemistry Central Journal 2017 11:95

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  27. Content type: Research article

    12N-benzyl matrinic acid analogues had been identified to be a novel scaffold of anti-HCV agents with a specific mechanism, and the representative compound 1 demonstrated a moderate anti-HCV activity. The intensi...

    Authors: Sheng Tang, Zong-Gen Peng, Ying-Hong Li, Xin Zhang, Tian-Yun Fan, Jian-Dong Jiang, Yan-Xiang Wang and Dan-Qing Song

    Citation: Chemistry Central Journal 2017 11:94

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  28. Content type: Research article

    Bioactive activities of adzuki bean have been widely reported, however, the phytochemical information of adzuki bean is incomplete. The aim of this study was to characterize and quantify flavonoids and saponin...

    Authors: Rui Liu, Zongwei Cai and Baojun Xu

    Citation: Chemistry Central Journal 2017 11:93

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  29. Content type: Research article

    The use of agricultural and food by-products is an economical solution to industrial biotechnology. The apricot press residues are abounding by-products from juice industry which can be used as substrates in s...

    Authors: Francisc Vasile Dulf, Dan Cristian Vodnar, Eva-Henrietta Dulf and Adela Pintea

    Citation: Chemistry Central Journal 2017 11:92

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  30. Content type: Research article

    The paper examines Co(II)–amino acid–imidazole systems (where amino acid = l-α-amino acid: alanine, asparagine, histidine) which, when in aqueous solutions, activate and reversibly take up dioxygen, while maintai...

    Authors: Marek Pająk, Magdalena Woźniczka, Andrzej Vogt and Aleksander Kufelnicki

    Citation: Chemistry Central Journal 2017 11:90

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  31. Content type: Research Article

    Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were ...

    Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Manikandan Selvaraj and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2017 11:89

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  32. Content type: Research article

    Suzuki C–C cross-coupling of aryl halides with aryl boronic acids using new phosphene-free palladium complexes as precatalysts was investigated. A pyridine-based Pd(II)-complex was used in open air under therm...

    Authors: Ismail I. Althagafi, Mohamed R. Shaaban, Aisha Y. Al-dawood and Ahmad M. Farag

    Citation: Chemistry Central Journal 2017 11:88

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  33. Content type: Research Article

    A general procedure for the synthesis of amides via the direct condensation of carboxylic acids and amines in the presence of TiCl4 is reported. The amidation reaction was performed in pyridine at 85 °C with a wi...

    Authors: Antonella Leggio, Jessica Bagalà, Emilia Lucia Belsito, Alessandra Comandè, Marianna Greco and Angelo Liguori

    Citation: Chemistry Central Journal 2017 11:87

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  34. Content type: Research article

    Lesinurad is a novel selective uric acid salt transport protein 1 (URAT1) inhibitor which is approved in the USA for the treatment of gout. However, there are some shortcomings among the reported synthetic rou...

    Authors: Qing Meng, Tong Zhao, Dongwei Kang, Boshi Huang, Peng Zhan and Xinyong Liu

    Citation: Chemistry Central Journal 2017 11:86

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  35. Content type: Research article

    A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR). All the synthesized compounds were evaluate...

    Authors: Abida Noor, Neelum Gul Qazi, Humaira Nadeem, Arif-ullah Khan, Rehan Zafar Paracha, Fawad Ali and Adil Saeed

    Citation: Chemistry Central Journal 2017 11:85

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  36. Content type: Research article

    Suoyang originates from a psammophyte named Cynomorium songaricum Rupr and has been known as a phenolic-antioxidant-enriched traditional Chinese herbal medicine. The present study atte...

    Authors: Yulu Xie, Xican Li, Jieying Xu, Qian Jiang, Hong Xie, Jianfeng He and Dongfeng Chen

    Citation: Chemistry Central Journal 2017 11:84

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  37. Content type: Research article

    Radezolid (RAD, 12), biaryl oxazolidinone, was synthesised with small modifications according to the methods described in the literature. The pharmacological activity is observed only for (S)-enantiomer, therefor...

    Authors: Katarzyna Michalska, Elżbieta Bednarek, Ewa Gruba, Kornelia Lewandowska, Mikołaj Mizera and Judyta Cielecka-Piontek

    Citation: Chemistry Central Journal 2017 11:82

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  38. Content type: Research article

    Typically, oxazolinyl metal complexes are synthesized in two steps, where the free ligand is prepared by the condensation reaction between a functionalized nitrile and an amino alcohol in the presence of a Lew...

    Authors: Mei Luo, Jing Cheng Zhang, Wen Min Pang and King Kuok Hii

    Citation: Chemistry Central Journal 2017 11:81

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    The Erratum to this article has been published in Chemistry Central Journal 2017 11:91

  39. Content type: Research article

    In the past few years, increased resistance of microorganisms towards antimicrobial agents become a serious health problem, so there is a need for the discovery of new antimicrobial agents. On the other hand, ...

    Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2017 11:80

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  40. Content type: Research article

    Tobacco smoke is a toxic gas-phase cocktail consisting of a broad range of organics, and free radical intermediates. The formation of smoke from a burning cigarette depends on a series of mechanisms, including...

    Authors: Audriy Jebet, Joshua Kibet, Lucy Ombaka and Thomas Kinyanjui

    Citation: Chemistry Central Journal 2017 11:79

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  41. Content type: Research article

    Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts. Chamomile extracts have fou...

    Authors: Maja Molnar, Nikolina Mendešević, Drago Šubarić, Ines Banjari and Stela Jokić

    Citation: Chemistry Central Journal 2017 11:78

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  42. Content type: Research article

    Two new symmetrical bis-thiourea, 2,2′-[{(terephthaloylbis(azanediyl)bis(carbonothioyl) bis(azanediyl)}dipropanoic acid] (1A) and 3,3′-[{(terephthaloylbis(azanediyl)bis (carbonothioyl)bis(azanediyl)} dipropano...

    Authors: Imran Fakhar, Bohari M. Yamin and Siti Aishah Hasbullah

    Citation: Chemistry Central Journal 2017 11:76

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  43. Content type: Meeting Report

    To showcase the Networks’ success during phase two (2012–2016), and to set out the strategy for phase three (2017–2019), the Directed Assembly Network held a meeting at the Royal Society in London, United King...

    Authors: J. A. R. Rose, P. R. Raithby and C. Makatsoris

    Citation: Chemistry Central Journal 2017 11:77

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  44. Content type: Research article

    The thiophene nucleus has been recognized as an important entity in the synthesis of heterocyclic compounds with promising pharmacological characteristics.

    Authors: Yahia Nasser Mabkhot, Nahed Ahmed Kaal, Seham Alterary, Salem S. Al-Showiman, Thoraya A. Farghaly and Mohammad S. Mubarak

    Citation: Chemistry Central Journal 2017 11:75

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  45. Content type: Research article

    Synthesis of 6-isomer of 5,8-O-dimethyl ether of shikonin (13), a promising anticancer scaffold, always remains a huge challenge. Herein a key intermediate for 13, 2-(1-hydroxyl-4-methyl-3-pentenyl)-1,4,5,8-tetra...

    Authors: Li Zhou, Xu Zhang and Wen Zhou

    Citation: Chemistry Central Journal 2017 11:74

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