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  1. Content type: Review

    Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heter...

    Authors: Sanjiv Kumar and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:38

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  2. Content type: Research Article

    Eugenol is the major component of clove essential oil and has demonstrated relevant biological potential with well-known antimicrobial and antioxidant action. Therefore, this work carried out the synthesis, pu...

    Authors: Francisco Felipe Maia da Silva, Francisco José Queiroz Monte, Telma Leda Gomes de Lemos, Patrícia Georgina Garcia do Nascimento, Alana Kelly de Medeiros Costa and Luanda Misley Mota de Paiva

    Citation: Chemistry Central Journal 2018 12:34

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  3. Content type: Research Article

    Flunarizine dihydrochloride (FLN) is used in the prophylactic treatment of migraine, vertigo, occlusive peripheral vascular disease and epilepsy. Cyclodextrins (CDs) are chiral, truncated cone shaped macrocycl...

    Authors: Santosh Kumar Upadhyay and Syed Mashhood Ali

    Citation: Chemistry Central Journal 2018 12:33

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  4. Content type: Research article

    Quantitative structure–activity relationship (QSAR) was carried out to study a series of aminooxadiazoles as PIM1 inhibitors having pki ranging from 5.59 to 9.62 (k i in nM)...

    Authors: Adnane Aouidate, Adib Ghaleb, Mounir Ghamali, Samir Chtita, Abdellah Ousaa, M’barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi

    Citation: Chemistry Central Journal 2018 12:32

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  5. Content type: Research Article

    Curcumin is one of the leading compound extracted from the dry powder of Curcuma longa (Zingiberaceae family), which possess several pharmacological properties. However, in vivo administration exhibited limited a...

    Authors: Siti Noor Hajar Zamrus, Muhammad Nadeem Akhtar, Swee Keong Yeap, Ching Kheng Quah, Wan-Sin Loh, Noorjahan Banu Alitheen, Seema Zareen, Saiful Nizam Tajuddin, Yazmin Hussin and Syed Adnan Ali Shah

    Citation: Chemistry Central Journal 2018 12:31

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  6. Content type: Research Article

    Design and synthesis of pyrazole-dimedone derivatives were described by one-pot multicomponent reaction as new antimicrobial agents. These new molecular framework were synthesized in high yields with a broad s...

    Authors: Assem Barakat, Abdullah M. Al-Majid, Bander M. Al-Qahtany, M. Ali, Mohamed Teleb, Mohamed H. Al-Agamy, Sehrish Naz and Zaheer Ul-Haq

    Citation: Chemistry Central Journal 2018 12:29

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  7. Content type: Research article

    Preservative effect of melanin-free extract of Sepia esculenta ink (MFESI) on Sparus latus fillet has been verified in our previous work. This study aims to further approach the mechanism of MFESI for extending t...

    Authors: Zhen-Hua Duan, Hua-Zhong Liu, Ping Luo, Yi-Peng Gu and Yan-Qun Li

    Citation: Chemistry Central Journal 2018 12:30

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  8. Content type: Research article

    This study explores the potential application of rice bran (agro waste) to nano-encapsulate phytase, which is a thermally unstable biologically active enzyme. Rice bran was converted to nanofibers (20–50 nm in...

    Authors: Upendra A. Rathnayake, Tharindu Senapathi, Chanaka Sandaruwan, Sanja Gunawardene, Veranja Karunaratne and Nilwala Kottegoda

    Citation: Chemistry Central Journal 2018 12:28

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  9. Content type: Research article

    A gas chromatography–mass spectrometry (GC–MS) method was validated for the determination of 16 polycyclic aromatic hydrocarbons (PAHs) from the FDA list of 93 harmful or potentially harmful constituents of ma...

    Authors: Jana Jeffery, Maria Carradus, Karolina Songin, Michael Pettit, Karl Pettit and Christopher Wright

    Citation: Chemistry Central Journal 2018 12:27

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  10. Content type: Research Article

    A set of different donor-π-acceptor compounds having dicyanovinyl as the acceptor and aryl moieties as donors were synthesized by Knoevenagel condensation. The UV–visible absorption and fluorescence spectra we...

    Authors: Mohie E. M. Zayed, Reda M. El-Shishtawy, Shaaban A. Elroby, Khalid O. Al-Footy and Zahra M. Al-amshany

    Citation: Chemistry Central Journal 2018 12:26

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  11. Content type: Research Article

    Apart from its numerous biological activities like antidiabetic, anti-inflammatory, antimicrobial, pyrazine moiety plays an important role in luminescent materials. Its role in luminescent materials is due to ...

    Authors: Mushtaq Ahmad, Zahida Perveen, Adailton J. Bortoluzzi, Shahid Hameed, Muhammad R. Shah, Muhammad Tariq, Ghias ud Din, Muhammad T. Jan, Muhammad Siddique and Muhammad Anwar

    Citation: Chemistry Central Journal 2018 12:25

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  12. Content type: Research Article

    In general, the greater the number of directly linked nitrogen atoms in a molecule, the better its energetic performance, while the stability will be accordingly lower. But 1,1ʹ-azobis-1,2,3-triazole (1) and 4,4ʹ...

    Authors: Chenhui Jia, Yuchuan Li, Shujuan Zhang, Teng Fei and Siping Pang

    Citation: Chemistry Central Journal 2018 12:22

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  13. Content type: Research

    Complexes of imidazole derivatives with transition metal ions have attracted much attention because of their biological and pharmacological activities, such as antimicrobial, antifungal, antiallergic, antitumo...

    Authors: Assila Maatar Ben Salah, Lilia Belghith Fendri, Thierry Bataille, Raquel P. Herrera and Houcine Naïli

    Citation: Chemistry Central Journal 2018 12:24

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  14. Content type: Research Article

    In this study, the contents of myricetrin, quercitrin and afzelin in Cercis chinensis leaves were determined simultaneously by 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM] BF4/70% ethanol microextraction ...

    Authors: Mengjun Shi, Nan He, Wenjing Li, Changqin Li and Wenyi Kang

    Citation: Chemistry Central Journal 2018 12:23

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  15. Content type: Research Article

    The molecular docking method was used to calculate the binding free energies between biphenyl dioxygenase and 209 polychlorinated biphenyl (PCB) congeners. The relationships between the calculated binding free...

    Authors: Xiao-Hui Zhao, Xiao-Lei Wang and Yu Li

    Citation: Chemistry Central Journal 2018 12:20

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  16. Content type: Research Article

    Clean water, which is free from pathogens and toxic chemicals, is vital to human health. The blue planet is encountering remarkable challenges in meeting the ever-increasing demands of clean water. The intenti...

    Authors: H. D. A. Chathumal Jayaweera, Induni Siriwardane, K. M. Nalin de Silva and Rohini M. de Silva

    Citation: Chemistry Central Journal 2018 12:18

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  17. Content type: Research Article

    The molecularly imprinted polymers for gallic acid were synthesized by precipitation polymerization. During the process of synthesis a non-covalent approach was used for the interaction of template and monomer...

    Authors: Showkat Ahmad Bhawani, Tham Soon Sen and Mohammad Nasir Mohammad Ibrahim

    Citation: Chemistry Central Journal 2018 12:19

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  18. Content type: Research Article

    In the recent years, the health benefits of the pigmented rice varieties have reported due to the presence of bioactive compounds. In this study, the phytochemical constituents (total phenolic, flavonoid and a...

    Authors: Ali Ghasemzadeh, Mohamad Taghi Karbalaii, Hawa Z. E. Jaafar and Asmah Rahmat

    Citation: Chemistry Central Journal 2018 12:17

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  19. Content type: Research Article

    This paper aims to study temperature-dependent quantitative structure activity relationship (QSAR) models of supercritical water oxidation (SCWO) process which were developed based on Arrhenius equation betwee...

    Authors: Ai Jiang, Zhiwen Cheng, Zhemin Shen and Weimin Guo

    Citation: Chemistry Central Journal 2018 12:16

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  20. Content type: Research Article

    Vitis heyneana is widely distributed in the north of Vietnam, it has been used in Vietnamese traditional medicine as an agent for treatment of arthritis, bronchitis, carbuncles and inflammatory conditions, and me...

    Authors: Do Thi Ha, Phung Thanh Long, Tran Thi Hien, Dao Trong Tuan, Nguyen Thi Thuy An, Nguyen Minh Khoi, Ha Van Oanh and Tran Manh Hung

    Citation: Chemistry Central Journal 2018 12:14

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  21. Content type: Research article

    The incorporation of two different monomers, having different properties, in the same polymer molecule leads to the formation of new materials with great scientific and commercial importance. The basic require...

    Authors: Ameen Hadi Mohammed, Mansor B. Ahmad, Nor Azowa Ibrahim and Norhazlin Zainuddin

    Citation: Chemistry Central Journal 2018 12:15

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  22. Content type: Commentary

    This commentary highlights the recent work published in journal Nature on the structural based discovery of novel analgesic compounds for opioid receptors with minimal effects. Manglik et al. selectively targe...

    Authors: Syed Lal Badshah, Asad Ullah, Salim S. Al-showiman and Yahia Nasser Mabkhot

    Citation: Chemistry Central Journal 2018 12:13

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  23. Content type: Research Article

    In the present study, a series of new hydrazone and sulfonamide derivatives of 1,2,4-triazole were synthesized. Initially three 4-substituted-5-(2-pyridyl)-1,2,4-triazole-3-thiones ZE-1(a–c) were treated with ...

    Authors: Waseem Khalid, Amir Badshah, Arif-ullah Khan, Humaira Nadeem and Sagheer Ahmed

    Citation: Chemistry Central Journal 2018 12:11

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  24. Content type: Research article

    Parkia speciosa seeds are a common ingredient in Malay cuisine with traditional interest because of its medicinal importance and content of health-promoting phytochemicals. This study evaluated the phytochemical ...

    Authors: Ali Ghasemzadeh, Hawa Z. E. Jaafar, Mohamad Fhaizal Mohamad Bukhori, Mohd Hafizad Rahmat and Asmah Rahmat

    Citation: Chemistry Central Journal 2018 12:12

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  25. Content type: Research article

    Thiol groups grafted silicon surface was prepared as previously described. 1H,1H,2H,2H-perfluorodecanethiol (PFDT) molecules were then immobilized on such a surface through disulfide bonds formation. To investiga...

    Authors: Xiaoning Zhang, Pei Gao, Valerie Hollimon, DaShan Brodus, Arion Johnson and Hongmei Hu

    Citation: Chemistry Central Journal 2018 12:10

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  26. Content type: Correction

    After publication of the original article [1], the following error was reported in the Results section of the Abstract: “antifungal activity against one yeast i.e. Aspergillus niger” should read: “antifungal acti...

    Authors: Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh and Baljeet Singh Saharan

    Citation: Chemistry Central Journal 2018 12:9

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    The original article was published in Chemistry Central Journal 2017 11:115

  27. Content type: Research Article

    Bioethanol obtained by fermenting cellulosic fraction of biomass holds promise for blending in petroleum. Cellulose hydrolysis yields glucose while hemicellulose hydrolysis predominantly yields xylose. Economi...

    Authors: Shalley Sharma, Anju Arora, Pankhuri Sharma, Surender Singh, Lata Nain and Debarati Paul

    Citation: Chemistry Central Journal 2018 12:8

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  28. Content type: Research article

    Relatively inexpensive, stable Schiff bases, namely 3-((4-hydroxybenzylidene)amino)-2-methylquinazolin-4(3H)-one (BZ3) and 3-((4-(dimethylamino)benzylidene)amino)-2-methylquinazolin-4(3H)-one (BZ4), were employed...

    Authors: Dalia M. Jamil, Ahmed K. Al-Okbi, Shaimaa B. Al-Baghdadi, Ahmed A. Al-Amiery, Abdulhadi Kadhim, Tayser Sumer Gaaz, Abdul Amir H. Kadhum and Abu Bakar Mohamad

    Citation: Chemistry Central Journal 2018 12:7

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  29. Content type: Research Article

    The Acanthaceae family is an important source of therapeutic drugs and ethno medicines. There are many famous medicinal plants from this family, such as Andrographis paniculata, Baphicacanthus cusia, and Diclipte...

    Authors: Bo Liu, Yanfang Yang, Hongbin Liu, Zhoutao Xie, Qun Li, Meng Deng, Fangping Li, Jingling Peng and Hezhen Wu

    Citation: Chemistry Central Journal 2018 12:6

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  30. Content type: Research Article

    Acacia hydaspica belongs to family leguminosae possess antioxidant, anti-inflammatory and anticancer activities. During our search for antioxidant compounds from A. hydaspica, we carried out bioassay guided fract...

    Authors: Tayyaba Afsar, Suhail Razak, Maria Shabbir and Muhammad Rashid Khan

    Citation: Chemistry Central Journal 2018 12:5

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  31. Content type: Research Article

    Ricinus communis (castor plant) is a potent medicinal plant, which is commonly used in the treatment of various ailments. The present study was conducted to appraise the cytotoxicity and mutagenicity of R. commun...

    Authors: Mazhar Abbas, Abid Ali, Muhammad Arshad, Asia Atta, Zahed Mehmood, Imtiaz Mahmood Tahir and Munawar Iqbal

    Citation: Chemistry Central Journal 2018 12:3

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  32. Content type: Research article

    Groundwater is considered as good alternative to potable water because of its low turbidity and perceived low contamination. The study assessed the physio-chemical and heavy metals concentrations in eight rand...

    Authors: Joshua Nosa Edokpayi, Abimbola Motunrayo Enitan, Ntwanano Mutileni and John Ogony Odiyo

    Citation: Chemistry Central Journal 2018 12:2

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  33. Content type: Research Article

    There is a dire need for the discovery and development of new antimicrobial agents after several experiments for a better resistance of microorganisms towards antimicrobial agents become a serious health probl...

    Authors: Bhookya Shankar, Pochampally Jalapathi, Balabadra Saikrishna, Shaym Perugu and Vijjulatha Manga

    Citation: Chemistry Central Journal 2018 12:1

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  34. Content type: Research Article

    The regioselective demethoxylation and dehalogenation of dihalogenated dibenzocyclooctadiene lignans derivatives were realized in a one-step reaction with excellent yields in the sodium and t-butanol reaction sys...

    Authors: Qing-yao Wang, Jia-qi Fang, Lu-lu Deng, Xiao-jiang Hao and Shu-zhen Mu

    Citation: Chemistry Central Journal 2017 11:138

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  35. Content type: Research Article

    A series of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides was synthesized and characterized by physicochemical and spectral means. The synthesized compounds were evaluated for ...

    Authors: Snehlata Yadav, Balasubramanian Narasimhan, Siong M. Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah and Manikandan Selvaraj

    Citation: Chemistry Central Journal 2017 11:137

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  36. Content type: Research article

    Masitinib (MST) is a selective tyrosine kinase inhibitor. Validated liquid chromatography tandem mass spectrometric method (LC–MS/MS) was developed for the quantification of MST in rat liver microsomes (RLMs) ...

    Authors: Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish and Mohamed W. Attwa

    Citation: Chemistry Central Journal 2017 11:136

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  37. Content type: Research Article

    Although poly(N-acyl dithieno[3,2-b:2′,3′-d]pyrrole)s have attracted great attention as a new class of conducting polymers with highly stabilized energy levels, hyperbranched polymers based on this monomer type ...

    Authors: Tam Huu Nguyen, Thu Anh Nguyen, Hoan Minh Tran, Le-Thu T. Nguyen, Anh Tuan Luu, Jun Young Lee and Ha Tran Nguyen

    Citation: Chemistry Central Journal 2017 11:135

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  38. Content type: Research Article

    The present investigation aimed to study and compare the efficiency of non-viable fungal isolates to remove divalent lead (Pb(II)) from aqueous streams. The selected fungal isolates showed identity with Aspergill...

    Authors: Kiran Aftab, Kalsoom Akhtar, Razia Noreen, Faiza Nazir and Umme Kalsoom

    Citation: Chemistry Central Journal 2017 11:133

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  39. Content type: Research Article

    Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and ph...

    Authors: Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam and Seema Zargar

    Citation: Chemistry Central Journal 2017 11:134

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  40. Content type: Research Article

    Dihydrofolate reductase (DHFR) is an important enzyme for de novo synthesis of nucleotides in Plasmodium falciparum and it is essential for cell proliferation. DHFR is a well known antimalarial target for drugs l...

    Authors: Mallika Pathak, Himanshu Ojha, Anjani K. Tiwari, Deepti Sharma, Manisha Saini and Rita Kakkar

    Citation: Chemistry Central Journal 2017 11:132

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  41. Content type: Research Article

    There is considerable interest in the chemical composition of smokeless tobacco products (STPs), owing to health concerns associated with their use. Previous studies have documented levels of 210Po, 210Pb and ura...

    Authors: K. McAdam, H. Kimpton, A. Porter, C. Liu, A. Faizi, M. Mola, J. McAughey and B. Rodu

    Citation: Chemistry Central Journal 2017 11:131

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  42. Content type: Research article

    Nitroaromatic and chloronitroaromatic compounds have been a subject of great interest in industry and recently in medical-pharmaceutic field. 2-Chloro-4-nitro/2-chloro-5-nitrobenzoic acids and 4-nitrobenzoic a...

    Authors: Manuela Crisan, Liliana Halip, Paulina Bourosh, Sergiu Adrian Chicu and Yurii Chumakov

    Citation: Chemistry Central Journal 2017 11:129

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  43. Content type: Research Article

    Human neutrophil elastase (HNE) is a potent serine protease belonging to the chymotrypsin family and is involved in a variety of pathologies affecting the respiratory system. Thus, compounds able to inhibit HN...

    Authors: Letizia Crocetti, Gianluca Bartolucci, Agostino Cilibrizzi, Maria Paola Giovannoni, Gabriella Guerrini, Antonella Iacovone, Marta Menicatti, Igor A. Schepetkin, Andrei I. Khlebnikov, Mark T. Quinn and Claudia Vergelli

    Citation: Chemistry Central Journal 2017 11:127

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  44. Content type: Research article

    Protein–protein interactions are responsible for many biological processes, and the study of how proteins undergo a conformational change induced by other proteins in the immobilized state can help us to under...

    Authors: Xiaoning Zhang and Hongmei Hu

    Citation: Chemistry Central Journal 2017 11:128

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  45. Content type: Research Article

    This study was conducted to develop fast and cost effective methods for the determination of caffeine in green coffee beans. In the present work direct determination of caffeine in aqueous solution of green co...

    Authors: Blen Weldegebreal, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2017 11:126

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  46. Content type: Research Article

    Theoretical simulations were designed by first principles approach of density functional theory to investigate the structural and optoelectronic properties of different structural classes of perylene; isolated...

    Authors: Mazmira Mohamad, Rashid Ahmed, Amirudin Shaari and Souraya Goumri-Said

    Citation: Chemistry Central Journal 2017 11:125

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  47. Content type: Research Article

    A simple solvent-free protocol for the preparation of flunixin, a potent non-narcotic, non-steroidal anti-inflammatory drugs is reported using boric acid as catalyst. Its salt, flunixin meglumine are then prep...

    Authors: Mahsa Yarhosseini, Shahrzad Javanshir, Zahra Dolatkhah and Mohammad G. Dekamin

    Citation: Chemistry Central Journal 2017 11:124

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